A sudden and mysterious inheritance brings Danny and his friends to Hobb Springs, a forgotten resort deep in the West Virginia hills. Hobb Springs is being looked after under the watchful care of Jackson and Sally, a socially awkward couple who introduce Danny to the long lost family he’s never known. A clan by the name of Hillicker. But soon Danny learns his relatives have a different way of living, that for generations, the Hillickers have observed ancient traditions rooted in cannibalism and other taboo rituals.

Simon Phoenix, a violent criminal cryogenically frozen in 1996, has escaped during a parole hearing in 2032 in the utopia of San Angeles. Police are incapable of dealing with his violent ways and turn to his captor, John Spartan, who had also been cryogenically frozen when wrongfully accused of killing 30 innocent people while apprehending Phoenix.

Ally Darling (Anna Faris) is realizing she’s a little lost in life. Her latest romance has just fizzled out, and she’s just been fired from her marketing job. Then she reads an eye-opening magazine article that warns that 96 percent of women who’ve been with 20 or more lovers are unlikely to find a husband. Determined to turn her life around and prove the article wrong, Ally embarks on a mission to find the perfect mate from among her numerous ex-boyfriends.

In 1865, a troop of Confederate soldiers led by Major Matt Stewart attack the wagon of gold escorted by Union cavalry and the soldiers are killed. The only wounded survivor tells that the war ended one month ago, and the group decides to take the gold and meet their liaison that knew that the war ended but did not inform the troop. The harsh Rolph Bainter kills the greedy man and the soldiers flee in his wagon driven by Major Stewart. When they meet a posse chasing them, Stewart gives wrong information to misguide the group; however, they have an accident with the wagon and lose the horses. They decide to stop a stagecoach and force the driver to transport them, but the posse returns and they are trapped in the station with the passenger. They realize that the men are not deputies and have no intention to bring them to justice but take the stolen gold.